The global mRNA technology market is expected to exhibit a marginal growth rate of 1.8% during the forecast period of 2022-2030. One of the major factors driving the market growth is the increased prevalence of medical disorders such as diabetes, tuberculosis (TB), cancer, and cardiovascular diseases (CVDs). The industry is also benefiting from the rising demand for therapeutic drugs and vaccines for COVID-19, Ebola, influenza, infectious and chronic diseases such as HIV, and other viral illnesses.
The recent COVID-19 outbreak has been a launching year for the mRNA technology platforms with the extensive use of mRNA vaccines for treating COVID-19. The market has observed skyrocketed sales of COVID-19 mRNA vaccines during 2020 and 2021. Moreover, the fact that mRNA vaccines hold much more potential than current prophylactic COVID-19 vaccines coupled with the soaring investments in the development of mRNA-based technologies and the perception that COVID-19 will continue to affect the global population, the market for mRNA technologies is expected to witness a steady decline in the few upcoming years.
However, with the commercial launch of a few mRNA products, the market is likely to observe a significant push at the end of the forecast period. Pharmaceutical companies are investing in mRNA technology as it allows them to mix numerous molecules into a therapeutic drug, technological advancements, extensive biotechnology research and development (R&D) efforts and advancements in healthcare technologies are some factors responsible for market expansion.
For instance, in June 2022, Pfizer Inc. announced to further strengthen its commitment to US manufacturing with a US$ 120 million investment at its Kalamazoo, Michigan, facility, enabling US-based production in support of its COVID-19 oral treatment, PAXLOVIDTM (nirmatrelvir [PF-07321332] tablets and ritonavir tablets). The investment will expand the production of active pharmaceutical ingredients (API) and registered starting materials (RSMs) used in the manufacture of nirmatrelvir, a novel main protease (Mpro) inhibitor originating in Pfizer’s laboratories.
The oncology segment holds a prominent share in the global mRNA technology market
The rise in the prevalence of cancer is expected to provide significant growth opportunities for the market during the forecast period. For instance, according to the World Health Organization (WHO), cancer is one of the leading causes of mortalities globally which accounted for around 10 million mortalities in 2020. Cancer-causing infections such as hepatitis and human papillomavirus are responsible for 30% of cancer cases in low and lower-middle-income countries. Moreover in 2021, according to the National Center for Health Statistics, 1,896,180 new cases cancer cases and 608,570 cancer mortalities were recorded in the US.
Owing to the increased number of cases, companies have been collaborating in an effort to provide better treatment to patients. For instance, in October 2017, Eli Lilly and Company and CureVac AG announced an immuno-oncology collaboration focused on the development and commercialization of up to five potential cancer vaccine products based on CureVac’s proprietary RNActive technology. The companies would use mRNA technology that targets tumor neoantigens for a more robust anti-cancer immune response. Thus, a rise in the prevalence of cancer coupled with the increasing efforts by the market players is anticipated to provide a significant push to segmental growth.
North America to contribute a significant share in the market
North America has enormous growth potential because of the large number of key players and the rapid increase in the number of patients in the US. In addition, increased investments and R&D efforts, a growing focus on precision medicine and novel therapeutics, a favorable regulatory environment, and an ever-increasing demand to produce transformational treatments are all contributing to the market expansion in North America. Moreover, Europe is expected to account for remarkable market growth due to a growth in clinical trials, research & development efforts, and superior technology. Furthermore, due to the development of healthcare facilities and a surge in infectious diseases, Asia-Pacific, Latin America, the Middle East & Africa are likely to experience significant growth.
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Market Structure and Competitive Landscape
The global mRNA technology market is competitive and consists of a number of global and regional players operating in the market. Pharmaceutical companies are investing in mRNA technology as it allows them to mix numerous molecules into a therapeutic drug, which is another important growth factor. The major companies in the market include Moderna Therapeutics, BioNTech, Ethris, CureVac, Argos Therapeutics, Sangamo Therapeutics Inc., Pfizer Inc, Biocon, Tiba Biotechnology, Verve Therapeutics Ltd. and many more. Diversified portfolios of leading firms in innovations and R&D activities characterize the global market, and they are likely to prioritize mergers and acquisitions, and collaborations. Recent developments observed in the market include,
- In June 2022, Pfizer Inc. announced to invest US$ 120 million in its Kalamazoo, Michigan, facility, enabling U.S.-based production in support of its COVID-19 oral treatment, PAXLOVIDTM (nirmatrelvir tablets and ritonavir tablets).
- In January 2022, Pfizer Inc. and BioNTech SE announced a new research, development, and commercialization collaboration to develop a potential first mRNA-based vaccine for the prevention of shingles (herpes zoster virus, or HZV), a debilitating, disfiguring, and painful disease. The collaboration builds on the companies’ success in developing the first approved and most widely used mRNA vaccine to help prevent COVID-19.
- In October 2021, Pfizer acquired an Emergency Use Authorization (EUA) from the US FDA for the Pfizer-BioNTech COVID-19 Vaccine for children aged 5 to 11.
Key Segmentation
RationalStat has segmented the global mRNA technology market based on product, manufacturing, application, end user, and region.
- By Product
- Prophylactic Vaccines
- Therapeutic Vaccines
- Therapeutics
- By Manufacturing
- In-House
- Outsourced
- By Application
- Oncology
- Respiratory Diseases
- Infectious Diseases
- Rare Diseases
- Others (Coronary Artery Diseases etc.)
- By End User
- Hospitals and Clinics
- Academic & Research Institutions
- By Region
- North America
- US
- Canada
- Latin America
- Brazil
- Mexico
- Rest of Latin America
- Western Europe
- Germany
- UK
- France
- Spain
- Italy
- Benelux
- Nordic
- Rest of Western Europe
- Eastern Europe
- Russia
- Poland
- Rest of Eastern Europe
- Asia Pacific
- China
- Japan
- India
- South Korea
- Australia
- ASEAN (Indonesia, Vietnam, Malaysia, etc.)
- Rest of Asia Pacific
- Middle East & Africa
- GCC
- South Africa
- Turkey
- Rest of the Middle East & Africa
- North America
Research Methodology
RationalStat has developed a state-of-the-art research methodology to crunch numbers and provide the best possible real-time insights to clients. We combine a varied range of industry experience, data analytics, and experts’ viewpoint to create a research methodology for market sizing and forecasting.
RationalStat combines a mix of secondary sources as well as primary research to assess the market size and develop a forecast. Key steps involved in accurately deriving the market numbers are:
- Defining the problem by understanding the type of market and data required by the client.
- Data gathering and collection through relevant paid databases, publicly available sources, company reports, annual reports, surveys, and interviews.
- Formulating a hypothesis to create market numbers, forecasts, influencing factors, and their relevance.
- Evaluating and analyzing the data by referring to data sources utilized and leveraged.
- Validating, interpreting, and finalizing the data by combining the details gathered from primary and secondary sources with the help of experienced analysts.
Secondary Sources
- Annual reports, company filings, investor presentations, product catalogs, and company documents
- Industry and market-related documents available in the public domain
- Paid database including Bloomberg, Factiva, S&P Capital IQ, FactSet, Refinitiv Eikon, ICIS, EUWID, and Thomson Reuters, among others
- Whitepapers, research papers, and industry blogs.
Why Buy this Report?
The report is intended for healthcare & life sciences companies, pharmaceutical companies, research organizations, government organizations, educational organizations, regulatory agencies, and market research firms, among others. The report provides an in-depth analysis of market size, consumption patterns, ongoing market trends and challenges, and future market opportunities. The report will serve as a source for a 360-degree analysis of the market thoroughly delivering insights to clients to find the right answers to their business questions.
Frequently Asked Questions (FAQs)
The global mRNA technology market is expected to grow at a CAGR of approximately 1.8% during the forecast period 2022-2028.
North America holds a prominent share of the global mRNA technology market.
The global market for mRNA technology was US$ 40 Billion in 2021.
The increasing prevalence of medical disorders and increased R&D investments are the major factors to influence the growth of the global mRNA technology market.
Major companies operating in the global mRNA technology market are Moderna Therapeutics, BioNTech, Ethris, CureVac, Argos Therapeutics, Sangamo Therapeutics Inc., Pfizer Inc, Biocon, Tiba Biotechnology, Verve Therapeutics Ltd. and many more.